Yesterday my 2001 c320 started to lose power then the check engine light started flashing and the car felt as if it was dying so i pulled over got my scanner and got the codes
P0301- cylinder 1 misfire
P0302 - cylinder 2 misfire
P0303- cylinder 3 misfire
P0304 - cylinder 4 misfire
P0300 - multiple misfire detected
P0221- throttle/pedal position sensor switch b circut range/performance
P0450 - evap emission system pressure sensor/switch
Current miles 100,000
Spark plugs done 2k miles ago

My guess is that is is some sort of fuel issue maybe the fuel pump
Any Thoughts?

 

Yeah, likely fuel pump. Get a fuel pressure gauge and hook it up to the fuel rail to confirm. Normal fuel pressure is around 56psi at all times.