I have a 2006 CLS 500.

I would like to upgrade to an AMG intercooler and heat exchanger with
the Johnson cm30 pump. Are these AMG components compatible with the
CLS 500? please Let me know Thanks!!!

An intercooler is only used with cars that are forced induction - turbo or supercharged. If your CLS500 is near standard, it will not be forced induction and will be naturally aspirated

I understand, i was thinking about converting to a 55 amg engine