I recently bought a 2010 E350..my question is can the 2015 E400 biturbo be mounted in the 2010 E350..my reason for the swap is I want twin turbo and every tubby I here about performance upgrades for Mercedes is extremely expensive

 

That would be a near impossible nightmare. This isn’t 1970

 

Cheaper to go buy a 2015 E400 and ell what you have

 

And I'm not sure why you picked the E400. The 2012-2014 E550 had more horsepower than the E400. You're better off selling the E350 and picking up a 2012+ E550. Those had the 402hp engine instead of the 382hp engine in the 2010-2011 E550. The E400 you're looking at had 329hp. You are at 268hp on the 2010, even the 2012+ E350 had the newer M276 engine which had 302hp. The only plus on the E400 is that it had a few more things as standard such as real leather instead of MB-tex like the E350. The 2014 E-550 was the last year for the E-550 so they're rarer and more money plus they had the face lift which 2012-2013 didn't have.

https://www.auto-brochures.com/mercedes_benz.html

Use this vin decoder so you don't end up with a base model car.

https://www.lastvin.com/

 

Agree, get E550. V8 is nicer than V6.

 

Yes, I agree . It would be not a cost effective way to tackle such a massive job

 

The easiest for you would be a M278 5.5 NA swap. It's not that difficult. The rest, with turbos and stuff, are.

 

Difficulty is relative... as prices of W212s keep dropping with age, we’ll see more and more interest in mods like this. Simply demographics.

When I was younger, I got a ‘80 300CD project car. Swapped out the original NA 3.0 5cyl diesel for a turbo variant and a 4spd out of a 240D. That was much simpler, no real electronics or coding to deal with.

To me, that was interesting since the combo didn’t exist in the US. A V-8 W212 is much more “pedestrian” and $/time easier to just acquire.