my 2018 560 is much noiser in the interior cabin than my former 2015 550. Noise is penetrating from somewhere into the passenger cabin either through the door / window seals or elsewhere. The 560 is nearly identical to my much quieter 550 with the exception of the pano roof.
Dealer service staff has arranged a meeting with the zone engineer. I believe you suggested this. Thx. A friend who owns Beverly Coachcraft in LA is thinking the exterior noise may be getting in thru the pano roof for various reasons; polymer glued on, less insulation, etc.
I’ll get to the bottom of it. Really ruining my ownership experience. I swear my SL65 has better exterior noise isolation. That’s just silly.

I too am under the impression the new S560 has more cabin noise than the pre facelift model. Almost sounds as if a window isn’t fully closed.

EXACTLY!!! I keep lifting up on the window controls to make sure they are fully closed.
I think it’s the pano roof. If not, door seals or window fitment.

Did you discuss with your dealer?

Not yet. I did european delivery and the car is currently enroute to stateside.

I was actually thinking about your car when I read Skerdian’s European Delivery details as he mentioned the same noise level change.

I have not experiened pano roof noise but everything is possible. You could try to identify and measure the noise intrusion by using an app on your phone. There are several apps to measure dB levels.
If not too risky you could hold the phone in various locations while driving and hopefully identify an exact location with the highest dB level.
Then go from there with driving a couple other ones. Perhaps grab a used pre-facelift from the dealer for a comparo.

The only noise I get from my Pano Roof in my 2015 is creaking. No wind noise at all. If what is reported here is a glitch in the 2018 models, IMO, that is a huge deal, but I can’t believe it isn’t a simple fix, once located.

I can’t believe it is anything more than a rubber weatherstrip or some such seal. The basic body of the FL car has not been changed at all. I believe that once your find the culprit seal and it is replaced, you’ll be fine. PLEASE keep us informed as to your progress and, hopefully your speedy resolution of this annoying problem.

And that’s because the new guy on the assembly isn’t German.

i will definitely update on this situation. I need it to get resolved. It’s ruining my enjoyment of the car. Certainly a trivial problem vs the never ending cascade of truly serious problems that are coming at alll of us all the time. Thanks to the many thoughtful contributors on this topic.

That article is almost 3 years old. Wonder if MB did anything to alleviate the problem?

Well, the one glimmer of hope out there, is that MB in Germany, and possibly in other markets—but not in the U.S.—is, for the first time since the W222 was launched, offering the long wheelbase model with the frigging Panorama Roof as optional. It had been standard equipment prior to MY18. I just don’t like the glass roof, because I don’t like the way it completely changes the look of lighter colored cars. However, I also don’t like the idea of a mass of glass sitting over my head. The fact that one of these things explodes every so often, for no apparent reason, isn’t comforting. They also creak, squeak and I virtually never use it. MB and other makers just NEED to make the glass roof OPTIONAL! Is that too much to ask?

Maybe when the S500 I6 model comes to the U.S., they will offer it without the Pano Roof, or maybe by MY19, they will make it optional across the entire line. One can only hope.

Stream, there will likely be no S500 i6 coming to the US anytime soon.
Expect the S450 to turn into the i6 model for MY19; that’s it.

Panorama roofs are technically sound and not noisier than steel roofs or moon roofs.
Strangely, our E63 is quieter than our prior S550 in terms of exterior noise or rattles. It feels extremely tight but has an optional acoustic package (some or much of which is part of the standard S).
Other E63 owners complain that it is too quiet as they like to hear more exchaust sound and the car is indeed the loudest sedan money can buy (from the outside).

As stated before I am not aware of any changes made to be panorama roof this 2014. Besides the optional Magic Sky, that is...

i am curious what your research will find. There may still be some manufacturing related changes, such as a part revision or change of vendor that will be extremely difficult to learn of unless it becomes part of a service bulletin.