Can you put 4 20”/8.5” rims on s450 4matic as opposed to 2 20”/8.5” and 2 20”/9.5” rims?

 

Sure you can. With the non omg package I believe the car comes with all four wheels being the same size with the amg styling package and wheels they are staggered and use wider tires in the rear.

 

Isn't the key variable with 4MATIC the tire diameter? One could select from many tire and wheel combinations and the computer wouldn't care as long as the front to rear tire diameters are close enough to each other.