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The 2014 CLS550 is a (different) biturbo as well. In a used premium (read: high maintenance) Mercedes that you intend to put that kind of mileage on, I'd be looking at a model with the 250 diesel or something with a naturally aspirated engine.
I feel like you are here to ruin my fun...lol! I will just go back to a Mustang if this is the case. I refuse to drive 2 hours a day in a car I am not enjoying in meantime and I can't change my commute distance/time. The miles per year I put on the car I feel is irrelevant. More so the mileage that these cars seem to start needing major repairs is the concern. My DD isn't an investment, it is an expense that I have a budget for. I just want to make sure I make the best financial decision regarding the individual car within a group of model options I prefer based on size, performance, mpg and reliability. As of now the consideration list includes the C63 and CLS 550. I started out looking at the CLS 63, but that would mean having to be OK with a 2012 or older car to stay in budget. Due the the speed of tech advancements I figured that wasn't the smartest choice.