Currently running 245/35 19 front and 275/30 19 on 19x 8.5 et33 and 19x 9.5 et38 vertini wheels.
I wanted to go with wider wheels 255/35 and 285/30 but not sure if it will rub.I also may want to lower the car in future. Has anyone tried this?.

I have those sizes on my 2014 E550 coupe. no issues

Nice I wonder if the facelift models have more area in the wheel wells. What type of tires and wheel offsets do you use?

I have Contintental Contisport Contac 5P SSR runflats on 19X8.5 and 19X9.5 rims.... 45mm offset front and 50 rear....Amg replicas... The bodies of the the facelift from 2014-2017 is the same as the 2010-2013 models. I had a 2010 E550 that I sold in Aug of 2015 to get my 2014 E550 in November of 2015. I had the same set up and offset but different rims

For some reason your pictures aren't showing anymore, but your offsets may be why you have no issues. I'm at 33et front and 38et rear do you think this would make a big difference?

Yes those offsets are of a too positive offset so that is why you will have clearance issues,, The rims will stick out too far

I ran 285/35/19 Mickey Thompson Drag radials with a slight fender rub on the outer edge of the tire (Only on hard acceleration). Not in the sidewall, so it wouldn't have killed the tires but made them look bad. 43 Offset was just enough to clear the little fender well flap. If you really want to run that, there are coil spring spacers to lift your car up that would work just fine. Just be careful, you have to maintain under a three percent rolling diameter difference in the front and rear or else it screw with the speed sensors and basically put it into limp mode.

235/40/19 in the front.