E-Class (W211) 2003-2009

2010 e350 - Major, intermittent misfiring, p0300 code

Thread Tools
 
Search this Thread
 
Rate Thread
 
Old Dec 12, 2022 | 12:05 PM
  #1  
MrChip's Avatar
Thread Starter
Newbie
 
Joined: Dec 2022
Posts: 5
Likes: 2
From: New Hampshire, USA
2010 Mercedes-Benz e350
2010 e350 - Major, intermittent misfiring, p0300 code

Hi everyone-
let me preface by saying I don't really know what i'm doing when it comes to autos - i'm capable, but uneducated on such matters
also, a layoff hit my household so taking it into the shop is less than ideal

driving a 2010 e350 base. It's doing a few funny things which my research led me to believe is a bad coil:

About half the time it's fine, no light, no chug, no loss of power, quiet idling at 500 rpm

Sometimes it'll idle weird when i start it, it'll bounce from 400 rpm to 1200 rpm and make a 'hair dryer' sound, itll do it for about 10 seconds and then it seems to 'find its timing' and settle into a nice, quiet idle

Other times, it throws a check light and i can feel a good chugging and a decent loss of power, in line with a single, consistent misfire

Then rarely, i'll start it and it'll feel like it's gonna explode. Check engine light does it's blinking bit. Heavy enough chugging to see the car shake from the outside, it just about doubles how much it shakea if you try putting it in gear.

So, i did my research, went to order my new coil and took it for an OBD2 test to identify the coil:
p0300 - random misfire detected

So it's definitely a misfire but for some reason the computer can't identify which piston? Does this rule out a coil? Any other relatively simple things i can try to diagnose this?
Lol should i just buy 5 more coils?
Reply
Old Dec 12, 2022 | 12:38 PM
  #2  
konigstiger's Avatar
Out Of Control!!
 
Joined: Jul 2003
Posts: 15,901
Likes: 4,632
From: North Scottsdale, AZ
'71 Pinto
212 should be posting here: https://mbworld.org/forums/e-class-w212-109/ have someone erase all stored codes and do a quick test using Xentry (MB diagnostics).
Reply
Old Dec 12, 2022 | 01:30 PM
  #3  
cetialpha5's Avatar
MBWorld Fanatic!
10 Year Member
 
Joined: Feb 2014
Posts: 6,190
Likes: 1,550
From: MA
2008 E350 4Matic, 2011 E350 4matic
Basic misfires are the spark plugs and then the coils and then if it's still there you start looking for other reasons. You should get a code scanner that does MB specific codes. Could be many other reasons but without the MB specific codes, could be anything. The 2010 is still the M272 engine which has intake manifold issues. You could have a pending code that doesn't show up on a regular OBDII scanner or it could be one of the sensors. Here's a cheap code scanner that does all MB specific codes and it's about $62 now.

Amazon Amazon
Reply
Old Dec 13, 2022 | 07:05 AM
  #4  
dvenneman's Avatar
Member
Photogenic
Liked
Loved
Community Favorite
 
Joined: Dec 2021
Posts: 192
Likes: 50
E350 4matic Wagon
Not enough info

Originally Posted by MrChip
Hi everyone-
let me preface by saying I don't really know what i'm doing when it comes to autos - i'm capable, but uneducated on such matters
also, a layoff hit my household so taking it into the shop is less than ideal

driving a 2010 e350 base. It's doing a few funny things which my research led me to believe is a bad coil:

About half the time it's fine, no light, no chug, no loss of power, quiet idling at 500 rpm

Sometimes it'll idle weird when i start it, it'll bounce from 400 rpm to 1200 rpm and make a 'hair dryer' sound, itll do it for about 10 seconds and then it seems to 'find its timing' and settle into a nice, quiet idle

Other times, it throws a check light and i can feel a good chugging and a decent loss of power, in line with a single, consistent misfire

Then rarely, i'll start it and it'll feel like it's gonna explode. Check engine light does it's blinking bit. Heavy enough chugging to see the car shake from the outside, it just about doubles how much it shakea if you try putting it in gear.

So, i did my research, went to order my new coil and took it for an OBD2 test to identify the coil:
p0300 - random misfire detected

So it's definitely a misfire but for some reason the computer can't identify which piston? Does this rule out a coil? Any other relatively simple things i can try to diagnose this?
Lol should i just buy 5 more coils?
start with telling us the mileage, how long you have owned it and what routine maintenance has been done

spark plugs need changed every 100k miles and some might say more - when you pull them is there oil on any of them. Note which ones if any.

If a plug is not torqued properly you can get a misfire

if a coil is not connected firmly you can get a misfire

if the camshaft magnets have not been changed that may need to be done

these cars have many jobs that can be done relatively inexpensively by yourself - but letting maintenance go or winging it piece by piece is going to create a migraine and cash exodus

Reply
Old Dec 13, 2022 | 11:20 AM
  #5  
MrChip's Avatar
Thread Starter
Newbie
 
Joined: Dec 2022
Posts: 5
Likes: 2
From: New Hampshire, USA
2010 Mercedes-Benz e350
Hey everyone,
Thanks for the replies.
Mileage is 123k, i've owned it since august and (as it was disclosed to me) the previous owner kept up on all annual maintenance with no major repairs late mileage maintenance.

I haven't been able to get into a shop that can run the MB diag but the kid who ran the codes last time seemed like a bit of a numbskull so I borrowed a friend's OBD2 and found out the tech i dealt with didn't know how to scroll through multiple codes

So the codes it's ACTUALLY throwing:
p0300 p0301 p0205 p0305 p0300 p0305 p0205 p0302

So the problem is at least as far down the system as my fuel injectors? Will update when i get the factory diagnostics.

I'm assuming my local MB dealer is gonna turn me away with no warranty?
Reply
Old Dec 14, 2022 | 10:29 AM
  #6  
Overheated's Avatar
Member
5 Year Member
Liked
Loved
Community Favorite
 
Joined: Feb 2017
Posts: 248
Likes: 36
From: L.A., Moscow, NYC, San Diego, Baja
1998 E320 Wagon, 2003 W211 E500, 2003 W211 E500, 1999 W210 E55 AMG
In addition to the electrical points offered above, if the misfire is intermittant isolated to a single cylender, first struck me as a fuel issue, injector perhaps.
Reply
Old Dec 14, 2022 | 10:57 AM
  #7  
cetialpha5's Avatar
MBWorld Fanatic!
10 Year Member
 
Joined: Feb 2014
Posts: 6,190
Likes: 1,550
From: MA
2008 E350 4Matic, 2011 E350 4matic
Originally Posted by Overheated
In addition to the electrical points offered above, if the misfire is intermittant isolated to a single cylender, first struck me as a fuel issue, injector perhaps.
Well according to his error codes, it's in 3 cylinders with one error in the fuel injector so in addition, I'd also check the fuel pressure and see if the fuel pump is good. And I'd also get a scanner that does MB specific codes that I mentioned before. There are probably other MB specific codes that are not showing up on a basic OBDII scanner that will better help to pinpoint the issue. Otherwise you're just throwing parts at the problem.
Reply

Currently Active Users Viewing This Thread: 1 (0 members and 1 guests)
 


You have already rated this thread Rating: Thread Rating: 0 votes,  average.


All times are GMT -4. The time now is 11:51 AM.

story-0
New Electric Mercedes-AMG GT 4-Door Coupe Unveiled: 10 Things You Need to Know

Slideshow: Mercedes-AMG's new electric GT 4-Door Coupe trades combustion for software, synthetic noise, and more than 1,100 horsepower.

By Verdad Gallardo | 2026-05-20 20:08:15


VIEW MORE
story-1
6 Mercedes Models That Did NOT Age Well (But Are Somehow Still Cool)

Slideshow: Not every Mercedes design becomes timeless, some feel stuck in the era they came from.

By Verdad Gallardo | 2026-05-12 18:09:07


VIEW MORE
story-2
Manual Mercedes? 6 Times Sindelfingen Let Drivers Have All The Fun

Slideshow: Yes, Mercedes built manual cars, and some of them are far more interesting than you'd expect.

By Verdad Gallardo | 2026-05-02 12:36:58


VIEW MORE
story-3
Mercedes SLR McLaren 722 S Is Extremely Rare Example Modified by McLaren

Slideshow: A one-of-one U.S.-spec Mercedes-Benz SLR McLaren Roadster became even rarer after a factory-backed transformation at McLaren's headquarters.

By Verdad Gallardo | 2026-04-29 11:19:28


VIEW MORE
story-4
8 Classic Boxy Mercedes Designs That Have Aged Like Fine Wine

Slideshow: Before curves took over, Mercedes mastered the art of the straight line, and some of those shapes still look right today.

By Verdad Gallardo | 2026-04-25 12:05:49


VIEW MORE
story-5
Flawlessly Restored Mercedes 190E Evo II Heads to Auction

Slideshow: The 190E Evolution II shows how a homologation necessity became a six-figure collector icon.

By Verdad Gallardo | 2026-04-22 17:53:47


VIEW MORE
story-6
Electric Mercedes C-Class Unveiled: 11 Things You Need to Know

Slideshow: Mercedes is turning one of its core nameplates electric, and the details show just how serious this shift is.

By Verdad Gallardo | 2026-04-21 13:58:06


VIEW MORE
story-7
Mercedes EQS Gets A Major Update: Everything You Need to Know

Slideshow: Faster charging, longer range, and a controversial steer-by-wire system define the latest evolution of Mercedes-Benz EQS.

By Verdad Gallardo | 2026-04-15 10:35:34


VIEW MORE
story-8
5 Underrated Mercedes-Benz Models That Don't Get the Love They Deserve

Slideshow: These overlooked Mercedes-Benz models never got the spotlight, but they quietly delivered more than most remember.

By Verdad Gallardo | 2026-04-13 19:35:45


VIEW MORE
story-9
Mercedes 300D Has Pushed Well Past 1 Million Miles and It Ain't Stopping

Slideshow: A well-used 1991 Mercedes-Benz 300D with more than one million miles is now looking for a new owner, and it still appears ready for more.

By Verdad Gallardo | 2026-04-10 10:05:15


VIEW MORE