2011 E350 upper Radiator Hose
I’d be 100% sure the hose was locking and then I’d probably grab a coolant pressure tester and verify the system pressure leading up to it blowing off. You can also pressurize the system with the tester and see if the hose holds. I don’t know the cap rating, minimum the system should hold, but at least 20psi it should hold.
Case in point - our rv is based on a chevy express 3500 chassis. Lower rad hose has the quick connect at the rad end. I used a decent brand - Gates - for all hoses. All except that one end were standard clamps. I could not get that quick connect to fit properly without needing to remove a couple thousands of material from inside the hose fitting. Replaced with OEM hose that fit perfectly. I know that Gates probably makes hoses for GM as original equipment but those would be first quality. Sometimes the after market mfg is considered second quality. I've also had OEM parts out of the box that were bad but very very seldom.
I'm assuming that coolant pressure at operating temp is ok. If either the hose fitting or the thermo housing is slightly out of spec, the internal pressure at operating temperature is causing the hose fitting to balloon just slightly enough to pop off. When you pull on the cold hose you are pulling straight out. When the engine is running the pressure is expanding the hose fitting outwards from inside. If the clip is barely in place you won't be able to pull it loose but the internal pressure can pop it loose.
So if the coolant pressure is ok - I said I assumed it was because you don't have an issue with coolant coming out the reservoir then the logical place to look is at the housing and/or the hose.
Case in point - our rv is based on a chevy express 3500 chassis. Lower rad hose has the quick connect at the rad end. I used a decent brand - Gates - for all hoses. All except that one end were standard clamps. I could not get that quick connect to fit properly without needing to remove a couple thousands of material from inside the hose fitting. Replaced with OEM hose that fit perfectly. I know that Gates probably makes hoses for GM as original equipment but those would be first quality. Sometimes the after market mfg is considered second quality. I've also had OEM parts out of the box that were bad but very very seldom.
I'm assuming that coolant pressure at operating temp is ok. If either the hose fitting or the thermo housing is slightly out of spec, the internal pressure at operating temperature is causing the hose fitting to balloon just slightly enough to pop off. When you pull on the cold hose you are pulling straight out. When the engine is running the pressure is expanding the hose fitting outwards from inside. If the clip is barely in place you won't be able to pull it loose but the internal pressure can pop it loose.
So if the coolant pressure is ok - I said I assumed it was because you don't have an issue with coolant coming out the reservoir then the logical place to look is at the housing and/or the hose.
Lets verify the parts first. I didn't want to rabbit hole, sometimes I think and post as myself, using only OE/OEM parts, checking the basics and now your stuck looking for more.
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- is the cooling fan operating correctly? At normal operating temp or with a.c. on it should be on low speed as commanded by ECU. At critical high temp it should switch to high speed.
- what does the oil look like? Should be clean with no chocolate milkshake appearance.
- any exhaust smell at the reservoir or any persistent white smoke out the tailpipe?
Not sure about the root cause of the overheat issue. From your description it seems that the hose has popped off before you've driven it long enough to verify overheat has been fixed?
Don't want to create a bigger scare but it's worth verifying both head gaskets are ok. Sometimes continued overheating is caused by exhaust leak into the coolant. Hopefully it's just a parts fitment issue.
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Reading back through your posts, I'm a bit confused because it sounds like you replaced certain components twice already... like the expansion tank cap and thermostat. Maybe consider reusing the original upper hose... if it stays on, the replacement hose could be the issue and if it pops off, the thermostat housing could be the issue. Assuming the original hose didn't pop off. Both our 2011 E350 and E550 have original coolant systems (100k miles +) and I wouldn't replace the hoses as they are still pliable, unless they started leaking.


