Every set-up is a little different. Just bank on rub... The problem is, You wont be able to fight the urge to go lower & lower. So chances are, your gonna rub...., the question will be, how much rub are you willing to live with. Do yourself a favor & dremel those fender tabs early, so they're perfectly flush. (last thing you need is to screw your tires up). Depending on rim width, offset, tire size, etc.. you MIGHT be fine.. BUT... You might still rub a little & need to roll your fenders. I've got 21's (9X21 Front, 10.5X21 rear, 45mm offset). Also have 10mm spacer Front, & 5mm Rear. I haven't rolled the fenders, but if I hit a decent dip in the road at high speeds, I get a little rub. Nothing major tho. In my situation, I wanted my wheels to sit out further than normal.. I've also found that my set-up eliminates the camber issue that other members suffer from. If your wheels sit inside the fenders, you might be fine with just removing the tabs & rolling. Good Luck..