Mercedes GLE450 Hybrid eqboost
I have an issue with two tablets, while i am driving they started blinking and right tablet switched off.
It says “Parking assistance and Parktronic inoperative” and parktronics starts beeping in red.
do you have any idea whats happened?

It could be something as simple as you hit a bug, but it's likely there is is a radar problem.

Um... tablets? You mean those screens? Picture one shows a driver's screen is off, picture two shows a passenger screen is off. Do you mean those? Very likely a software issue.

Or is that just your camera shutter as the screen is flickering (60?) (unknown frames per second):
https://mbworld.org/forums/gle-class...ent-black.html
https://mbworld.org/forums/gls-class...ent-black.html
https://mbworld.org/forums/gle-class...black-out.html

If these, there was a software update that likely got pushed via OTA that caused it, a fix should be out though.

As for parking assist or parktronic inoperative, could it be this? https://mbworld.org/forums/gle-class...n-backing.html

yeah exactly screens blinking and turned off while driving

no sometimes it is happening as a result of washing the car and when the car is dry from water all is okay, but my issue is different

If the screen is turning off while driving that is caused by the buggy software, I am not sure which is the fixed version and which is the buggy one, the best course of action is to get it updated at a dealership as the screens turning off can be a safety issue. There is also no timeline on when you will get the OTA fixed version so to immediately solve it, it will require a dealership personnel hooking the computer to XENTRY.

The other end of the spectrum is actual hardware failure of the screen, yes I heard forum members reporting having to replace the entire screen but most of them was a software issue, this particular software issue affected different MB models, I heard EQS also affected reported on the forums, it is a bad OTA update in that case that got pushed to different MB models.